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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62088
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2ry2
Name: purinergic receptor P2Y2
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium

Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]

Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium]

PMID:17003265
affects response to substanceISORGD:623806480464CTDP2RY2 protein affects the susceptibility to Calcium

PMID:18343036
multiple interactionsISORGD:13524866480464CTD[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium

PMID:11527950
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.