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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736050
Species: Mus musculus
RGD Object: Gene
Symbol: Gpx4
Name: glutathione peroxidase 4
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases response to substanceEXP 6480464CTDGPX4 results in decreased susceptibility to Cadmium

PMID:18206984
increases expressionISORGD:692266480464CTDCadmium results in increased expression of GPX4 mRNA

PMID:25388156
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.