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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735404
Species: Homo sapiens
RGD Object: Gene
Symbol: ALB
Name: albumin
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALBaffects bindingEXP 6480464CTDALB protein binds to Cadmium; Cadmium binds to ALB proteinPMID:17274600 PMID:23896426
ALBincreases expressionEXP 6480464CTDCadmium results in increased expression of ALB proteinPMID:22027495
ALBdecreases expressionISOAlb (Rattus norvegicus)6480464CTDCadmium results in decreased expression of ALB mRNAPMID:17327699
ALBdecreases secretionISOAlb (Rattus norvegicus)6480464CTDCadmium results in decreased secretion of ALB proteinPMID:15772367
ALBmultiple interactionsISOAlb (Mus musculus)6480464CTDALB protein inhibits the reaction [Cadmium results in increased phosphorylation of and results in decreased activity of DLD protein]PMID:27289041
ALBmultiple interactionsISOAlb (Rattus norvegicus)6480464CTD[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of ALB protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]PMID:24923654 PMID:25240712 PMID:30090589
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