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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734437
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSB
Name: cathepsin B
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSBmultiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA]; NUPR1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA]PMID:31319114
CTSBmultiple interactionsISOCtsb (Mus musculus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB proteinPMID:31862506
CTSBmultiple interactionsISOCtsb (Rattus norvegicus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased cleavage of CTSB protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSB mRNA; brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased cleavage of CTSB protein]; brusatol inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSB mRNA]; NFE2L2 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased cleavage of CTSB protein]; NFE2L2 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CTSB mRNA]PMID:34695510
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