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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69473
Species: Homo sapiens
RGD Object: Gene
Symbol: SREBF1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SREBF1multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SREBF1 mRNAPMID:36602393
SREBF1decreases expressionISOSrebf1 (Rattus norvegicus)6480464CTDCadmium results in decreased expression of SREBF1 mRNAPMID:28315714
SREBF1multiple interactionsISOSrebf1 (Rattus norvegicus)6480464CTD[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein]PMID:25240712
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