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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bnip3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDCadmium results in increased expression of BNIP3 protein

PMID:24824807
increases expressionISORGD:13509136480464CTDCadmium results in increased expression of BNIP3 mRNA, Cadmium results in increased expression of BNIP3 protein

PMID:24824807
increases expressionISORGD:7338146480464CTDCadmium results in increased expression of BNIP3 protein

PMID:24824807
multiple interactionsISORGD:13509136480464CTDpyrazolanthrone inhibits the reaction [Cadmium results in increased expression of BNIP3 protein], U 0126 inhibits the reaction [Cadmium results in increased expression of BNIP3 protein]

PMID:24824807
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.