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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ocln
Name: occludin
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDCadmium results in decreased expression of OCLN mRNA

PMID:28829631
decreases expressionISORGD:16240786480464CTDCadmium results in decreased expression of OCLN protein

PMID:26424772
multiple interactionsISORGD:16240786480464CTDflavocoxid inhibits the reaction [Cadmium results in decreased expression of OCLN protein]

PMID:26424772
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.