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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352888
Species: Homo sapiens
RGD Object: Gene
Symbol: AKR1C3
Name: aldo-keto reductase family 1 member C3
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKR1C3increases expressionEXP 6480464CTDCadmium results in increased expression of AKR1C3 mRNAPMID:21120746
AKR1C3multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C3 mRNAPMID:29741670 PMID:31738976 PMID:35301059
AKR1C3decreases expressionISOAkr1c18 (Mus musculus)6480464CTDCadmium results in decreased expression of AKR1C18 mRNAPMID:24067728
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