GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | increases expression | EXP | | 6480464 | CTD | Cadmium results in increased expression of HSPA1A mRNA; Cadmium results in increased expression of HSPA1A protein | PMID:16729991 PMID:17244614 PMID:21172416 PMID:22562489 PMID:24284285 PMID:33559965 PMID:8917683 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSPA1A mRNA; Cadmium promotes the reaction [HSF1 protein binds to HSPA1A enhancer]; Cadmium promotes the reaction [HSF1 protein binds to HSPA1A promoter] | PMID:16460681 PMID:17244614 PMID:31738976 | HSPA1A | increases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | Cadmium results in increased expression of HSPA1A protein | PMID:16729991 | HSPA1A | multiple interactions | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA1A mRNA | PMID:37325564 | |
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