GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP12 | multiple interactions | EXP | | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased cleavage of and results in increased activity of CASP12 protein]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein]; Cadmium results in increased cleavage of and results in increased activity of CASP12 protein | PMID:19442655 PMID:37300854 | CASP12 | increases activity | ISO | Casp12 (Mus musculus) | 6480464 | CTD | Cadmium results in increased activity of CASP12 protein | PMID:20600546 | | ||||||||||||||||||||||
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