GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ppargc1a | increases expression | EXP | | 6480464 | CTD | Cadmium results in increased expression of PPARGC1A mRNA | PMID:26187450 | Ppargc1a | increases acetylation | ISO | PPARGC1A (Homo sapiens) | 6480464 | CTD | Cadmium results in increased acetylation of PPARGC1A protein | PMID:25159133 | Ppargc1a | multiple interactions | ISO | PPARGC1A (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A mRNA; luzindole inhibits the reaction [Melatonin inhibits the reaction [Cadmium results in increased acetylation of PPARGC1A protein]]; Melatonin inhibits the reaction [Cadmium results in increased acetylation of PPARGC1A protein]; sirtinol inhibits the reaction [Melatonin inhibits the reaction [Cadmium results in increased acetylation of PPARGC1A protein]] | PMID:25159133 PMID:35301059 | Ppargc1a | multiple interactions | ISO | Ppargc1a (Rattus norvegicus) | 6480464 | CTD | [cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein; puerarin inhibits the reaction [[cadmium acetate results in increased abundance of Cadmium] which results in decreased expression of PPARGC1A protein] | PMID:33404196 | | ||||||||||||||||||||||
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