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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsn
Name: gelsolin
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsnaffects localizationEXP 6480464CTDCadmium affects the localization of GSN proteinPMID:22553113
Gsnaffects bindingISOGSN (Homo sapiens)6480464CTDGSN protein binds to CadmiumPMID:23896426
Gsndecreases expressionISOGSN (Homo sapiens)6480464CTDCadmium results in decreased expression of GSN mRNAPMID:17547211
Gsnincreases oxidationISOGsn (Mus musculus)6480464CTDCadmium results in increased oxidation of GSN proteinPMID:24077948
Gsnmultiple interactionsISOGSN (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GSN proteinPMID:33040242
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