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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10765
Species: Mus musculus
RGD Object: Gene
Symbol: Igf1
Name: insulin-like growth factor 1
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Igf1decreases expressionEXP 6480464CTDCadmium results in decreased expression of IGF1 mRNAPMID:22666406
Igf1multiple interactionsEXP 6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IGF1 mRNAPMID:29373603 PMID:31614173 PMID:31904401
Igf1multiple interactionsISOIGF1 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1 mRNA; Cadmium promotes the reaction [IGF1 protein binds to IGF1R protein]PMID:35301059 PMID:9648927
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