GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | increases expression | ISO | RGD:1350913 | 6480464 | CTD | bafilomycin A1 results in increased expression of BNIP3 mRNA, bafilomycin A1 results in increased expression of BNIP3 protein | PMID:25981168 | multiple interactions | ISO | RGD:1350913 | 6480464 | CTD | BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein], Erlotinib Hydrochloride inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein], gefitinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 protein], HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA], lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA] | PMID:25981168 | | ||||||||||||||||||||||
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