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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733100
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2
Name: BCL2 apoptosis regulator
Acc ID: CHEBI:22689
Term: bafilomycin A1
Definition: The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus.
Chemical ID: MESH:C040929
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2decreases expressionISOBcl2 (Mus musculus)6480464CTDbafilomycin A1 results in decreased expression of BCL2 mRNAPMID:31310755
BCL2multiple interactionsISOBcl2 (Rattus norvegicus)6480464CTDbafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]PMID:34374793
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