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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:21759
Term: N-methyl-N'-nitro-N-nitrosoguanidine
Definition: An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position
Chemical ID: MESH:D008769
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:25826480464CTDMethylnitronitrosoguanidine results in increased expression of ESR2 mRNA, Methylnitronitrosoguanidine results in increased expression of ESR2 protein

PMID:21628965, PMID:22330348
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.