GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | multiple interactions | EXP | | 6480464 | CTD | Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] | PMID:17440993 PMID:18205790 PMID:20737476 | Ptgs2 | decreases expression | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Glucosamine results in decreased expression of PTGS2 mRNA | PMID:20737476 | Ptgs2 | decreases glycosylation | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Glucosamine results in decreased glycosylation of PTGS2 protein | PMID:22089456 | Ptgs2 | increases expression | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | Glucosamine analog results in increased expression of PTGS2 protein alternative form | PMID:19656660 | Ptgs2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] | PMID:20737476 | Ptgs2 | multiple interactions | ISO | PTGS2 (Homo sapiens) | 6480464 | CTD | [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] | PMID:12681956 PMID:17605605 | |
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