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REFERENCE - CHEMICAL INTERACTIONS REPORT

RGD ID: 15036816
Species: All species
RGD Object: Reference
Acc ID: CHEBI:207229
Term: dihydroartemisinin
Definition: A sesquiterpenoid compound which is used as a drug for treatment of malaria.
Chemical ID: MESH:C039060
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]

 
Cpt1amultiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]

 
Fgf19multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]

 
Nfkbiamultiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver]

 
Nr0b2multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]

 
Nr1h4multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]

 
Pparamultiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]

 
Slc10a1multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Slc10a1 protein in liver]

 
Cyp7a1multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]

 
Fasmultiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver]

 
Nfkb1multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of NF-kB protein in liver]

 
Nlrp3multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver]

 
Srebf1multiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver]

 
Tnfmultiple interactionsEXP 15036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Tnf protein in liver]

 
NLRP3multiple interactionsISORGD:130831415036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver]

 
Nlrp3multiple interactionsISORGD:130831415036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Nrlp3 protein in liver]

 
CPT1Amultiple interactionsISORGD:239615036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]

 
Cpt1amultiple interactionsISORGD:239615036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of CPT1a mRNA and protein in liver]

 
CYP7A1multiple interactionsISORGD:248215036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]

 
Cyp7a1multiple interactionsISORGD:248215036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]

 
NFKBIAmultiple interactionsISORGD:317115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver]

 
Nfkbiamultiple interactionsISORGD:317115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nfkbia protein in liver]

 
PPARAmultiple interactionsISORGD:336915036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]

 
Pparamultiple interactionsISORGD:336915036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Ppara mRNA and protein in liver]

 
SLC10A1multiple interactionsISORGD:368115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Slc10a1 protein in liver]

 
Slc10a1multiple interactionsISORGD:368115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Slc10a1 protein in liver]

 
TNFmultiple interactionsISORGD:387615036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Tnf protein in liver]

 
Tnfmultiple interactionsISORGD:387615036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Tnf protein in liver]

 
FASmultiple interactionsISORGD:61983115036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver]

 
Fasmultiple interactionsISORGD:61983115036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Fas mRNA and protein in liver]

 
ABCB11multiple interactionsISORGD:61993015036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]

 
Abcb11multiple interactionsISORGD:61993015036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Abcb11 protein in liver]

 
FGF19multiple interactionsISORGD:62016615036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]

 
Fgf15multiple interactionsISORGD:62016615036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of FGF19 protein in liver and intestine]

 
NR0B2multiple interactionsISORGD:62103215036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]

 
Nr0b2multiple interactionsISORGD:62103215036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr0b2 protein in liver and intestine]

 
NR1H4multiple interactionsISORGD:62883115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]

 
Nr1h4multiple interactionsISORGD:62883115036816RGDDihydroartemisinin inhibits the reaction [ethanol decreases expression of Nr1h4 mRNA and protein in liver and liver cell nuclei and intestine]

 
SREBF1multiple interactionsISORGD:6942315036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver]

 
Srebf1multiple interactionsISORGD:6942315036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of Srebf1 mRNA and protein in liver]

 
NFKB1multiple interactionsISORGD:7049815036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of NF-kB protein in liver]

 
Nfkb1multiple interactionsISORGD:7049815036816RGDDihydroartemisinin inhibits the reaction [ethanol increases expression of NF-kB protein in liver]

 
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