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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621664
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zfp423
Name: zinc finger protein 423
Acc ID: CHEBI:205919
Term: clobetasol
Definition: A 3-oxo-Δ1,Δ4-steroid that is 16β-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11β and 17α positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17α-propionate ester to treat various skin disorders, including exzema and psoriasis.
Chemical ID: MESH:D002990
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp423decreases expressionISOZfp423 (Mus musculus)6480464CTDClobetasol results in decreased expression of ZFP423 mRNAPMID:27462272
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