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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68433
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aqp9
Name: aquaporin 9
Acc ID: CHEBI:2038
Term: 5-azacytidine
Definition: An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.
Chemical ID: MESH:D001374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aqp9increases expressionISORGD:7355056480464CTDAzacitidine results in increased expression of AQP9 mRNA

PMID:25953102
Aqp9multiple interactionsISORGD:7355056480464CTD[Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]

PMID:25953102
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