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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309080
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gadd45b
Name: growth arrest and DNA-damage-inducible, beta
Acc ID: CHEBI:2038
Term: 5-azacytidine
Definition: An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.
Chemical ID: MESH:D001374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gadd45bmultiple interactionsISORGD:13192206480464CTDAzacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B]

PMID:18225533
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