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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332089
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase family 1, subfamily A1
Acc ID: CHEBI:196991
Term: 4-hydroperoxycyclophosphamide
Definition: A phosphorodiamide that is the active metabolite of the nitrogen mustard cyclophosphamide. It has potent antineoplastic and immunosuppressive properties.
Chemical ID: MESH:C011272
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases response to substanceISOALDH1A1 (Homo sapiens)6480464CTDALDH1A1 protein results in decreased susceptibility to perfosfamidePMID:16614850 PMID:8662658
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