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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69328
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
Acc ID: CHEBI:19363
Term: 2,5-bis(aziridin-1-yl)-1,4-benzoquinone
Definition: A member of the class of 1,4-benzoquinones that is p-benzoquinone in which the hydrogens at positions 2 and 5 are replaced by aziridin-1-yl groups.
Chemical ID: MESH:C009970
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdkn1aincreases expressionISORGD:7353416480464CTDethylenimine quinone results in increased expression of CDKN1A mRNA ethylenimine quinone results in increased expression of CDKN1A protein

PMID:8943236 PMID:9343371 PMID:9586815
Cdkn1amultiple interactionsISORGD:7353416480464CTDAcetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA]

PMID:8943236
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