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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731729
Species: Mus musculus
RGD Object: Gene
Symbol: Casp1
Name: caspase 1
Acc ID: CHEBI:188567
Term: Belnacasan
Definition: null
Chemical ID: MESH:C520022
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp1decreases activityEXP 6480464CTDbelnacasan results in decreased activity of CASP1 proteinPMID:31070765
Casp1multiple interactionsEXP 6480464CTDbelnacasan inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CASP1 protein]PMID:31070765
Casp1decreases activityISOCasp1 (Rattus norvegicus)6480464CTDbelnacasan results in decreased activity of CASP1 proteinPMID:34935985
Casp1multiple interactionsISOCASP1 (Homo sapiens)6480464CTDbelnacasan inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]PMID:30205151
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