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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737011
Species: Mus musculus
RGD Object: Gene
Symbol: Hand1
Name: heart and neural crest derivatives expressed 1
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hand1decreases expressionEXP 6480464CTDNicotine results in decreased expression of HAND1 proteinPMID:31507073
Hand1decreases expressionISOHand1 (Rattus norvegicus)6480464CTDNicotine results in decreased expression of HAND1 mRNA; Nicotine results in decreased expression of HAND1 proteinPMID:24368670
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