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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733129
Species: Mus musculus
RGD Object: Gene
Symbol: Vim
Name: vimentin
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vimmultiple interactionsEXP 6480464CTDNicotine promotes the reaction [Quartz results in increased expression of VIM protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of VIM protein]PMID:36868510
Vimdecreases expressionISOVIM (Homo sapiens)6480464CTDNicotine results in decreased expression of VIM mRNAPMID:18247414
Vimincreases expressionISOVIM (Homo sapiens)6480464CTDNicotine results in increased expression of VIM mRNA; Nicotine results in increased expression of VIM proteinPMID:18844224 PMID:23219715
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