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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1603713
Species: Homo sapiens
RGD Object: Gene
Symbol: KNG1
Name: kininogen 1
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KNG1decreases activityISOKng1 (Rattus norvegicus)6480464CTDNicotine results in decreased activity of KNG1 protein alternative formPMID:7807204
KNG1multiple interactionsISOKng1 (Rattus norvegicus)6480464CTDCapsaicin promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form]; Kainic Acid promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form]PMID:7807204
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