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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343014
Species: Homo sapiens
RGD Object: Gene
Symbol: MIR15B
Name: microRNA 15b
Acc ID: CHEBI:18723
Term: nicotine
Definition: A racemate composed of equimolar amounts of (R)- and (S)-nicotine.
Chemical ID: MESH:D009538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MIR15Bdecreases expressionISOMir15b (Mus musculus)6480464CTDNicotine results in decreased expression of MIR15B mRNAPMID:33640489
MIR15Bincreases methylationISOMir15b (Mus musculus)6480464CTDNicotine results in increased methylation of MIR15B genePMID:33640489
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