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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737416
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2C19
Name: cytochrome P450 family 2 subfamily C member 19
Acc ID: CHEBI:1864
Term: 4-hydroxycyclophosphamide
Definition: A phosphorodiamide that consists of 2-amino-1,3,2-oxazaphosphinan-4-ol 2-oxide having two 2-chloroethyl groups attached to the exocyclic nitrogen.
Chemical ID: MESH:C012358
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2C19multiple interactionsEXP 6480464CTD[CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamidePMID:30500380
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