GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | App | increases chemical synthesis | ISO | APP (Homo sapiens) | 6480464 | CTD | APP gene mutant form results in increased chemical synthesis of Superoxides | PMID:22886847 | App | multiple interactions | ISO | APP (Homo sapiens) | 6480464 | CTD | 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidine inhibits the reaction [APP gene mutant form results in increased chemical synthesis of Superoxides]; GW 501516 inhibits the reaction [APP gene mutant form results in increased chemical synthesis of Superoxides]; resveratrol inhibits the reaction [APP protein results in increased abundance of Superoxides] | PMID:16212921 PMID:22886847 | | ||||||||||||||||||||||
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