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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621422
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh5a1
Name: aldehyde dehydrogenase 5 family, member A1
Acc ID: CHEBI:18421
Term: superoxide
Definition: An oxygen radical that has formula O2.
Chemical ID: MESH:D013481
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh5a1multiple interactionsISOAldh5a1 (Mus musculus)6480464CTD[ALDH5A1 gene mutant form results in increased susceptibility to 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo(h)(1,6)naphthyridin-2(1H)-one] which results in increased abundance of Superoxides; [ALDH5A1 gene mutant form results in increased susceptibility to NCS 382] which results in increased abundance of SuperoxidesPMID:29031482
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