Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737156
Species: Mus musculus
RGD Object: Gene
Symbol: Foxo1
Name: forkhead box O1
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxo1increases activityISOFOXO1 (Homo sapiens)6480464CTDAICA ribonucleotide results in increased activity of FOXO1 proteinPMID:25065674
Foxo1increases expressionISOFOXO1 (Homo sapiens)6480464CTDAICA ribonucleotide results in increased expression of FOXO1 proteinPMID:25065674
Foxo1increases phosphorylationISOFOXO1 (Homo sapiens)6480464CTDAICA ribonucleotide results in increased phosphorylation of FOXO1 proteinPMID:25065674
Foxo1multiple interactionsISOFOXO1 (Homo sapiens)6480464CTDAICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]; AICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of SOD2 mRNA]PMID:25065674
Go Back to source page   Continue to Ontology report