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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733442
Species: Mus musculus
RGD Object: Gene
Symbol: Eif4ebp1
Name: eukaryotic translation initiation factor 4E binding protein 1
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4ebp1multiple interactionsEXP 6480464CTDAICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]PMID:15806154
Eif4ebp1decreases phosphorylationISOEif4ebp1 (Rattus norvegicus)6480464CTDAICA ribonucleotide results in decreased phosphorylation of EIF4EBP1 proteinPMID:28041982
Eif4ebp1multiple interactionsISOEif4ebp1 (Rattus norvegicus)6480464CTDAICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]PMID:21195169
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