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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620517
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xpo1
Name: exportin 1
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xpo1multiple interactionsISOXPO1 (Homo sapiens)6480464CTDAICA ribonucleotide promotes the reaction [ABL1 protein mutant form binds to XPO1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to BECN1 protein]; AICA ribonucleotide promotes the reaction [XPO1 protein binds to YWHAQ protein]PMID:33070465
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