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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344166
Species: Homo sapiens
RGD Object: Gene
Symbol: OPA1
Name: OPA1 mitochondrial dynamin like GTPase
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OPA1multiple interactionsISOOpa1 (Rattus norvegicus)6480464CTDAICA ribonucleotide inhibits the reaction [Acetaminophen results in decreased expression of OPA1 protein]; AICA ribonucleotide inhibits the reaction [Diclofenac results in decreased expression of OPA1 protein]PMID:27792760
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