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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730815
Species: Mus musculus
RGD Object: Gene
Symbol: P2rx7
Name: purinergic receptor P2X, ligand-gated ion channel, 7
Acc ID: CHEBI:18388
Term: apigenin
Definition: A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells.
Chemical ID: MESH:D047310
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2rx7multiple interactionsISOP2rx7 (Rattus norvegicus)6480464CTDApigenin inhibits the reaction [Freund's Adjuvant results in increased expression of P2RX7 protein]PMID:25935278
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