GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adra2a | affects abundance | EXP | | 6480464 | CTD | ADRA2A protein affects the abundance of Norepinephrine | PMID:20083574 | Adra2a | affects binding | EXP | | 6480464 | CTD | Norepinephrine binds to ADRA2A protein | PMID:10336518 | Adra2a | multiple interactions | EXP | | 6480464 | CTD | [ADRA2A protein mutant form co-treated with ADRA2C protein mutant form] results in increased abundance of Norepinephrine | PMID:20083574 | Adra2a | affects secretion | ISO | Adra2a (Rattus norvegicus) | 6480464 | CTD | ADRA2A protein affects the secretion of Norepinephrine | PMID:11312645 | Adra2a | multiple interactions | ISO | Adra2a (Rattus norvegicus) | 6480464 | CTD | [BRL 44408 binds to and results in decreased activity of ADRA2A protein] inhibits the reaction [Xylazine inhibits the reaction [Potassium results in increased secretion of Norepinephrine]] | PMID:11312645 | Adra2a | multiple interactions | ISO | ADRA2A (Homo sapiens) | 6480464 | CTD | 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Dexmedetomidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Doxazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Norepinephrine binds to and results in increased activity of ADRA2A protein; Norepinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; Prazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; talipexole inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Yohimbine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] | PMID:10742289 PMID:20030735 | | ||||||||||||||||||||||
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