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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621375
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ikbkb
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Acc ID: CHEBI:18320
Term: 1,4-dithiothreitol
Definition: The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkbmultiple interactionsISOIKBKB (Homo sapiens)6480464CTDDithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]]PMID:20584749
Ikbkbmultiple interactionsISOIkbkb (Mus musculus)6480464CTDDithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of IKBKB protein]; Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein]]PMID:17067557
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