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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2806
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmox1
Name: heme oxygenase 1
Acc ID: CHEBI:18320
Term: 1,4-dithiothreitol
Definition: The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:107176480464CTDDithiothreitol inhibits the reaction [farrerol results in increased expression of HMOX1 protein]

PMID:26111761
multiple interactionsISORGD:7309016480464CTDDithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]

PMID:24489685
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.