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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319194
Species: Homo sapiens
RGD Object: Gene
Symbol: STAT6
Name: signal transducer and activator of transcription 6
Acc ID: CHEBI:18320
Term: 1,4-dithiothreitol
Definition: The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STAT6multiple interactionsISOStat6 (Mus musculus)6480464CTDDithiothreitol inhibits the reaction [Asbestos, Serpentine promotes the reaction [polyethylene glycol-superoxide dismutase results in increased oxidation of STAT6 protein]]; Dithiothreitol inhibits the reaction [Asbestos, Serpentine promotes the reaction [Polyethylene Glycols results in increased oxidation of STAT6 protein]]; Dithiothreitol inhibits the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]; Dithiothreitol inhibits the reaction [polyethylene glycol-superoxide dismutase results in increased oxidation of STAT6 protein]; Dithiothreitol inhibits the reaction [Polyethylene Glycols results in increased oxidation of STAT6 protein]; Dithiothreitol inhibits the reaction [SOD1 protein affects the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]]PMID:26699812
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