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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620890
Species: Mus musculus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP-binding cassette, sub-family B member 1A
Acc ID: CHEBI:18313
Term: alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide
Definition: A glycotriaosylceramide having alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucose as the trisaccharide component.
Chemical ID: MESH:C018549
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases chemical synthesisISOABCB1 (Homo sapiens)6480464CTDABCB1 protein results in increased chemical synthesis of globotriaosylceramidePMID:14662772
Abcb1amultiple interactionsISOABCB1 (Homo sapiens)6480464CTDCyclosporine inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased chemical synthesis of globotriaosylceramide]PMID:14662772
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