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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730886
Species: Homo sapiens
RGD Object: Gene
Symbol: CREB1
Name: cAMP responsive element binding protein 1
Acc ID: CHEBI:18295
Term: histamine
Definition: A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.
Chemical ID: MESH:D006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CREB1decreases phosphorylationEXP 6480464CTDHistamine results in decreased phosphorylation of CREB1 proteinPMID:29452068
CREB1multiple interactionsEXP 6480464CTDGlycyrrhizic Acid inhibits the reaction [Histamine results in decreased phosphorylation of CREB1 protein]; prolinedithiocarbamate inhibits the reaction [Histamine results in decreased phosphorylation of CREB1 protein]PMID:29452068
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