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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621621
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Taar1
Name: trace-amine-associated receptor 1
Acc ID: CHEBI:18295
Term: histamine
Definition: A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.
Chemical ID: MESH:D006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Taar1increases activityISOTaar1 (Mus musculus)6480464CTDHistamine results in increased activity of TAAR1 proteinPMID:19725810
Taar1multiple interactionsISOTaar1 (Mus musculus)6480464CTD[Histamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMPPMID:19725810
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