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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732368
Species: Homo sapiens
RGD Object: Gene
Symbol: NTF3
Name: neurotrophin 3
Acc ID: CHEBI:18291
Term: manganese atom
Definition: A manganese group element atom that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NTF3multiple interactionsEXP 6480464CTDNTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTRK3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of CREB1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK1 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of MAPK3 protein]; NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]PMID:31676349
NTF3multiple interactionsISONtf3 (Mus musculus)6480464CTD[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of NTF3 protein]PMID:31676349
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