GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BDNF | multiple interactions | EXP | | 6480464 | CTD | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein | PMID:32659473 | BDNF | decreases expression | ISO | Bdnf (Mus musculus) | 6480464 | CTD | Manganese results in decreased expression of BDNF protein | PMID:25099302 | BDNF | decreases expression | ISO | Bdnf (Rattus norvegicus) | 6480464 | CTD | Manganese results in decreased expression of BDNF mRNA; Manganese results in decreased expression of BDNF protein | PMID:25099302 PMID:29205667 PMID:31161640 | BDNF | multiple interactions | ISO | Bdnf (Rattus norvegicus) | 6480464 | CTD | [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]; Rolipram inhibits the reaction [Manganese results in decreased expression of BDNF protein] | PMID:17827730 PMID:30951808 PMID:31161640 | | ||||||||||||||||||||||
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