GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | INSR | multiple interactions | EXP | | 6480464 | CTD | [Manganese co-treated with Magnesium co-treated with INS protein] results in increased phosphorylation of and results in increased activity of INSR protein; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein modified form]; [Polylysine co-treated with Manganese co-treated with Magnesium] promotes the reaction [INS protein results in increased phosphorylation of and results in increased activity of INSR protein] | PMID:2542339 | INSR | decreases expression | ISO | Insr (Rattus norvegicus) | 6480464 | CTD | Manganese deficiency results in decreased expression of INSR protein | PMID:2204694 | INSR | multiple interactions | ISO | Insr (Rattus norvegicus) | 6480464 | CTD | [Manganese co-treated with INS1 protein] results in increased phosphorylation of INSR protein | PMID:1321133 | | ||||||||||||||||||||||
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