GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MT2A | affects abundance | EXP | | 6480464 | CTD | MT2A gene SNP affects the abundance of Iron | PMID:21328412 | MT2A | multiple interactions | EXP | | 6480464 | CTD | [Deferoxamine results in decreased abundance of Iron] which results in increased expression of MT2A mRNA; [ferric ammonium citrate results in decreased abundance of Iron] which results in increased expression of MT2A mRNA; [Hemin results in decreased abundance of Iron] which results in increased expression of MT2A mRNA | PMID:12393473 | MT2A | increases expression | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | Iron deficiency results in increased expression of MT2A mRNA | PMID:16629162 | MT2A | increases expression | ISO | Mt2 (Mus musculus) | 6480464 | CTD | Iron deficiency results in increased expression of MT2 mRNA | PMID:24089420 | MT2A | multiple interactions | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | [Zinc co-treated with Iron] results in increased expression of and affects the localization of MT2A protein; Iron results in increased expression of and affects the localization of MT2A protein | PMID:17241390 | |
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