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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621433
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc25a14
Name: solute carrier family 25 member 14
Acc ID: CHEBI:18243
Term: dopamine
Definition: Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.
Chemical ID: MESH:D004298
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc25a14decreases response to substanceISOSLC25A14 (Homo sapiens)6480464CTDSLC25A14 protein results in decreased susceptibility to DopaminePMID:20600837
Slc25a14increases expressionISOSLC25A14 (Homo sapiens)6480464CTDDopamine results in increased expression of SLC25A14 mRNAPMID:20600837
Slc25a14multiple interactionsISOSLC25A14 (Homo sapiens)6480464CTDDactinomycin inhibits the reaction [Dopamine results in increased expression of SLC25A14 mRNA]; SLC25A14 protein inhibits the reaction [Dopamine results in increased abundance of Superoxides]PMID:20600837
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