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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10529
Species: Mus musculus
RGD Object: Gene
Symbol: Ephx1
Name: epoxide hydrolase 1, microsomal
Acc ID: CHEBI:18135
Term: catechol
Definition: A benzenediol comprising of a benzene core carrying two hydroxy substituents ortho to each other.
Chemical ID: MESH:C034221
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ephx1multiple interactionsISOEphx1 (Rattus norvegicus)6480464CTDEPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]PMID:8211999
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