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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61928
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:18088
Term: formononetin
Definition: A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'.
Chemical ID: MESH:C007768
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1aincreases expressionISORGD:7309356480464CTDformononetin results in increased expression of HIF1A mRNA

PMID:21309574
Hif1amultiple interactionsISORGD:7309356480464CTDformononetin results in increased expression of and results in decreased degradation of HIF1A protein

PMID:21309574
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